Resultados: 25

Effect of curcumin on acute chronic kidney disease due to ischemia-reperfusion syndrome

Rev. Esc. Enferm. USP; 56 (spe), 2022
ABSTRACT Objective: To evaluate the effect of curcumin on renal function, hemodynamics, and renal oxidative profile of rats with chronic kidney disease (CKD) subjected to renal ischemia-reperfusion injury (IRI). Methods: Wistar rats, 250-300 g, distributed in four groups: Sham (n = 5), CKD simulation; ...

Infectious events in kidney transplant recipients from deceased expanded criteria donors: a prospective cohort

Rev. Esc. Enferm. USP; 55 (), 2021
ABSTRACT Objective: Analyze risk factors for infection in kidney transplant recipients from deceased expanded criteria donors (DECD) in the first two years of follow-up. Method: This is a prospective cohort study with 466 patients from DECD who underwent kidney transplantation in 2015 and 2016 in Brazi...

Efeito da Justicia acuminatissima, Sara Tudo do Amazonas, na injúria renal aguda isquêmica: estudo experimental

Rev. Esc. Enferm. USP; 53 (), 2019
RESUMO Objetivo Avaliar o efeito da Justicia acuminatissima , Sara Tudo do Amazonas, na função renal, na hemodinâmica renal, no perfil oxidativo e na histologia renal em ratos com injúria renal aguda isquêmica. Método Ensaio pré-clínico com ratos Wistar, adultos, machos (250-350 g), distribu...

Diabetes Mellitus: fator de risco para toxicidade de medicamentos

Rev. Esc. Enferm. USP; 52 (), 2018
RESUMO Objetivo Avaliar o efeito do antibiótico gentamicina em modelo experimental na presença de Diabetes Mellitus por meio da função renal e perfil oxidativo. Método Ratos Wistar, adultos, machos, foram distribuídos nos grupos: Citrato; Gentamicina (Genta), (gentamicina 100 mg/kg de peso corp...

Sepsis-induced acute kidney injury: kidney protection effects by antioxidants

Rev. bras. enferm; 71 (4), 2018
ABSTRACT Objective: To evaluate the antioxidant action of N-acetylcysteine and diosmin-hesperidin in an experimental model of sepsis-induced acute kidney injury in rats. Methods: The study used 20 Wistar adult male rats divided into the following groups: control (laparotomy with no induction of abdomin...

Nursing Activities Score and Acute Kidney Injury

Rev. bras. enferm; 70 (3), 2017
ABSTRACT Objective: to evaluate the nursing workload in intensive care patients with acute kidney injury (AKI). Method: A quantitative study, conducted in an intensive care unit, from April to August of 2015. The Nursing Activities Score (NAS) and Kidney Disease Improving Global Outcomes (KDIGO) were u...

Prevenção da nefrotoxicidade da anfotericina B por meio do uso de fitomedicamentos

Rev. Esc. Enferm. USP; 49 (spe), 2015
RESUMO Objetivo Avaliar ação renoprotetora dos flavonoides diosmina e hesperidina na prevenção da nefrotoxicidade da anfotericina B em modelo experimental com ratos. Método Ratos Wistar, adultos, machos foram distribuídos nos seguintes grupos: Salina; diosmina hesperidina (animais receberam 50 mg/k...

Antioxidant protection of statins in acute kidney injury induced by sepsis

Rev. Esc. Enferm. USP; 48 (5), 2014
Objective Evaluating the effect of preconditioning with simvastatin in acute kidney injury induced by sepsis. Method Male adult Wistar rats were divided into the following groups: SHAM (control); SHAM+Statin (0.5 mg/kg simvastatin, orally); Sepsis (cecal puncture ligation – CPL); Sepsis+Statin. Phy...

Nephrotoxicity Of Polymyxin B: Experimental Study In Cells And Implications For Nursing Practice

Rev. Esc. Enferm. USP; 48 (2), 2014
The aim of the study was to characterize the cell damage mechanisms involved in the pathophysiology of cytotoxicity of polymyxin B in proximal tubular cells (LLC - PK1) and discuss about the nurses interventions to identify at risk patients and consider prevention or treatment of nephrotoxicity acute kid...