Rev. Enferm. Atual In Derme; 95 (36), 2021
Publication year: 2021
Objetivo:
Compreender as manifestações clínicas neurológicas apresentadas por pacientes com coronavírus da Síndrome Respiratória Aguda Grave 2 (SARS-CoV-2)/Doença Coronavírus 19 (COVID-19).Métodos:
Trata-se de revisão integrativa, conduzida em junho de 2020, com base na pergunta norteadora “Quais as manifestações neurológicas apresentadas por pacientes com SARS-CoV-2/COVID-19?, elaborada a partir da estratégia PICO. A combinação de palavras “SARS-CoV-2” AND “COVID-19” AND “neurologic manifestations” foi utilizada na busca em bases de dados Cumulative Index to Nursing and Allied Health Literature (CINAHL), National Library of Medicine (PubMed), Scopus e Web of Science. Resultados:
Dos 6 artigos incluídos, 4 constavam na PubMed e todos tinham sido publicados em periódicos internacionais. Dentre as manifestações observadas, as disfunções olfativas e gustativas foram as que se destacaram. Outras manifestações observadas envolveram desde a mialgia, dor de cabeça e tontura à encefalite e Síndrome de Guillain-Barré. Conclusão:
Manifestações neurológicas estão presentes em pacientes com SARS-CoV-2/COVID-19, incluindo aqueles não hospitalizados, destacando as disfunções olfativas e gustativas. Estas podem estar associadas a um quadro de COVID-19 precoce e severo, sendo, portanto, importante o seu reconhecimento na infecção. Apesar da ocorrência dessas manifestações, ainda se faz necessária a investigação dos mecanismos patogênicos e progressão da doença no contexto do Sistema Nervoso Central (SNC) e Periférico (SNP).
Objective:
To understand the clinical neurological manifestations of patients with Coronavirus of Severe Acute Respiratory Syndrome 2 (SARS-CoV-2)/Coronavirus 19 (COVID-19). Methods:
This integrative review was conducted in June 2020, based on the guiding question “What are the neurological manifestations presented by patients with SARS-CoV-2/COVID-19?, based on the PICO strategy.The combination of words “SARS-CoV-2” AND “COVID-19” AND “neurologic manifestations” was used in the search in databases Cumulative Index to Nursing and Allied Health Literature (CINAHL), National Library of Medicine (PubMed), Scopus, and Web of Science.Results:
Of the six articles included, four were in PubMed, and all had been published in international journals. Among the manifestations observed, olfactory and gustatory disorders stood out. Other manifestationsobserved ranged from myalgia, headache, and dizziness to encephalitis and Guillain-Barré syndrome.Conclusion:
Neurological manifestations are present in patients with SARS-CoV-2/COVID-19, including those not hospitalized, highlighting olfactory and tastedisorders. These may be associated with early and severe COVID-19, and its recognition in infection is therefore essential. Despite the occurrence of these manifestations, it is still necessary to investigate the pathogenic mechanisms and progression of the disease in the context of the Central Nervous System (CNS) and Peripheral (PNS).
